diff --git a/composer.json b/composer.json
index 25d8974dfe..77b8c2b379 100644
--- a/composer.json
+++ b/composer.json
@@ -125,7 +125,7 @@
         "cache/integration-tests": "dev-master",
         "composer/package-versions-deprecated": "^1.8",
         "doctrine/annotations": "^1.12",
-        "doctrine/cache": "~1.6",
+        "doctrine/cache": "^1.6|^2.0",
         "doctrine/collections": "~1.0",
         "doctrine/data-fixtures": "^1.1",
         "doctrine/dbal": "^2.10|^3.0",
diff --git a/src/Symfony/Bridge/Doctrine/composer.json b/src/Symfony/Bridge/Doctrine/composer.json
index 6e7384341c..75db8e99e7 100644
--- a/src/Symfony/Bridge/Doctrine/composer.json
+++ b/src/Symfony/Bridge/Doctrine/composer.json
@@ -45,7 +45,6 @@
         "symfony/translation": "^4.4|^5.0",
         "symfony/var-dumper": "^4.4|^5.0",
         "doctrine/annotations": "^1.10.4",
-        "doctrine/cache": "~1.6",
         "doctrine/collections": "~1.0",
         "doctrine/data-fixtures": "^1.1",
         "doctrine/dbal": "^2.10|^3.0",
diff --git a/src/Symfony/Bundle/FrameworkBundle/CacheWarmer/AnnotationsCacheWarmer.php b/src/Symfony/Bundle/FrameworkBundle/CacheWarmer/AnnotationsCacheWarmer.php
index b339dee4d0..8ff2416d80 100644
--- a/src/Symfony/Bundle/FrameworkBundle/CacheWarmer/AnnotationsCacheWarmer.php
+++ b/src/Symfony/Bundle/FrameworkBundle/CacheWarmer/AnnotationsCacheWarmer.php
@@ -54,13 +54,10 @@ class AnnotationsCacheWarmer extends AbstractPhpFileCacheWarmer
         }
 
         $annotatedClasses = include $annotatedClassPatterns;
-
-        if (class_exists(PsrCachedReader::class)) {
-            // doctrine/annotations:1.13 and above
-            $reader = new PsrCachedReader($this->annotationReader, $arrayAdapter, $this->debug);
-        } else {
-            $reader = new CachedReader($this->annotationReader, new DoctrineProvider($arrayAdapter), $this->debug);
-        }
+        $reader = class_exists(PsrCachedReader::class)
+            ? new PsrCachedReader($this->annotationReader, $arrayAdapter, $this->debug)
+            : new CachedReader($this->annotationReader, new DoctrineProvider($arrayAdapter), $this->debug)
+        ;
 
         foreach ($annotatedClasses as $class) {
             if (null !== $this->excludeRegexp && preg_match($this->excludeRegexp, $class)) {
diff --git a/src/Symfony/Bundle/FrameworkBundle/DependencyInjection/Compiler/UnusedTagsPass.php b/src/Symfony/Bundle/FrameworkBundle/DependencyInjection/Compiler/UnusedTagsPass.php
index 5558e3cfe8..0ca7eb17d5 100644
--- a/src/Symfony/Bundle/FrameworkBundle/DependencyInjection/Compiler/UnusedTagsPass.php
+++ b/src/Symfony/Bundle/FrameworkBundle/DependencyInjection/Compiler/UnusedTagsPass.php
@@ -92,6 +92,7 @@ class UnusedTagsPass implements CompilerPassInterface
         'validator.auto_mapper',
         'validator.constraint_validator',
         'validator.initializer',
+        'workflow.definition',
     ];
 
     public function process(ContainerBuilder $container)
diff --git a/src/Symfony/Bundle/FrameworkBundle/Resources/config/annotations.php b/src/Symfony/Bundle/FrameworkBundle/Resources/config/annotations.php
index a880b75a8b..cec9f9499f 100644
--- a/src/Symfony/Bundle/FrameworkBundle/Resources/config/annotations.php
+++ b/src/Symfony/Bundle/FrameworkBundle/Resources/config/annotations.php
@@ -62,14 +62,16 @@ return static function (ContainerConfigurator $container) {
                 param('kernel.debug'),
             ])
 
+        ->set('annotations.cache_adapter', PhpArrayAdapter::class)
+            ->factory([PhpArrayAdapter::class, 'create'])
+            ->args([
+                param('kernel.cache_dir').'/annotations.php',
+                service('cache.annotations'),
+            ])
+
         ->set('annotations.cache', DoctrineProvider::class)
             ->args([
-                inline_service(PhpArrayAdapter::class)
-                    ->factory([PhpArrayAdapter::class, 'create'])
-                    ->args([
-                        param('kernel.cache_dir').'/annotations.php',
-                        service('cache.annotations'),
-                    ]),
+                service('annotations.cache_adapter')
             ])
             ->tag('container.hot_path')
 
diff --git a/src/Symfony/Bundle/FrameworkBundle/Tests/CacheWarmer/AnnotationsCacheWarmerTest.php b/src/Symfony/Bundle/FrameworkBundle/Tests/CacheWarmer/AnnotationsCacheWarmerTest.php
index 80bb7acc31..d5a018aa03 100644
--- a/src/Symfony/Bundle/FrameworkBundle/Tests/CacheWarmer/AnnotationsCacheWarmerTest.php
+++ b/src/Symfony/Bundle/FrameworkBundle/Tests/CacheWarmer/AnnotationsCacheWarmerTest.php
@@ -44,13 +44,16 @@ class AnnotationsCacheWarmerTest extends TestCase
         $this->assertFileExists($cacheFile);
 
         // Assert cache is valid
-        $psr6Cache = new PhpArrayAdapter($cacheFile, new NullAdapter());
-        if (class_exists(PsrCachedReader::class)) {
-            $reader = new PsrCachedReader($this->getReadOnlyReader(), $psr6Cache);
-        } else {
-            $reader = new CachedReader($this->getReadOnlyReader(), new DoctrineProvider($psr6Cache));
-        }
-
+        $reader = class_exists(PsrCachedReader::class)
+            ? new PsrCachedReader(
+                $this->getReadOnlyReader(),
+                new PhpArrayAdapter($cacheFile, new NullAdapter())
+            )
+            : new CachedReader(
+                $this->getReadOnlyReader(),
+                new DoctrineProvider(new PhpArrayAdapter($cacheFile, new NullAdapter()))
+            )
+        ;
         $refClass = new \ReflectionClass($this);
         $reader->getClassAnnotations($refClass);
         $reader->getMethodAnnotations($refClass->getMethod(__FUNCTION__));
@@ -67,13 +70,19 @@ class AnnotationsCacheWarmerTest extends TestCase
         $this->assertFileExists($cacheFile);
 
         // Assert cache is valid
-        $psr6Cache = new PhpArrayAdapter($cacheFile, new NullAdapter());
-        if (class_exists(PsrCachedReader::class)) {
-            $reader = new PsrCachedReader($this->getReadOnlyReader(), $psr6Cache);
-        } else {
-            $reader = new CachedReader($this->getReadOnlyReader(), new DoctrineProvider($psr6Cache));
-        }
-
+        $phpArrayAdapter = new PhpArrayAdapter($cacheFile, new NullAdapter());
+        $reader = class_exists(PsrCachedReader::class)
+            ? new PsrCachedReader(
+                $this->getReadOnlyReader(),
+                $phpArrayAdapter,
+                true
+            )
+            : new CachedReader(
+                $this->getReadOnlyReader(),
+                new DoctrineProvider($phpArrayAdapter),
+                true
+            )
+        ;
         $refClass = new \ReflectionClass($this);
         $reader->getClassAnnotations($refClass);
         $reader->getMethodAnnotations($refClass->getMethod(__FUNCTION__));
diff --git a/src/Symfony/Bundle/FrameworkBundle/Tests/Functional/AutowiringTypesTest.php b/src/Symfony/Bundle/FrameworkBundle/Tests/Functional/AutowiringTypesTest.php
index b122390036..39707a7e09 100644
--- a/src/Symfony/Bundle/FrameworkBundle/Tests/Functional/AutowiringTypesTest.php
+++ b/src/Symfony/Bundle/FrameworkBundle/Tests/Functional/AutowiringTypesTest.php
@@ -34,7 +34,11 @@ class AutowiringTypesTest extends AbstractWebTestCase
         static::bootKernel();
 
         $annotationReader = self::getContainer()->get('test.autowiring_types.autowired_services')->getAnnotationReader();
-        $this->assertInstanceOf(class_exists(PsrCachedReader::class) ? PsrCachedReader::class : CachedReader::class, $annotationReader);
+        if (class_exists(PsrCachedReader::class)) {
+            $this->assertInstanceOf(PsrCachedReader::class, $annotationReader);
+        } else {
+            $this->assertInstanceOf(CachedReader::class, $annotationReader);
+        }
     }
 
     public function testEventDispatcherAutowiring()
diff --git a/src/Symfony/Bundle/FrameworkBundle/composer.json b/src/Symfony/Bundle/FrameworkBundle/composer.json
index c878111b2f..3417c7ce64 100644
--- a/src/Symfony/Bundle/FrameworkBundle/composer.json
+++ b/src/Symfony/Bundle/FrameworkBundle/composer.json
@@ -34,7 +34,7 @@
     },
     "require-dev": {
         "doctrine/annotations": "^1.10.4",
-        "doctrine/cache": "~1.0",
+        "doctrine/cache": "^1.0|^2.0",
         "doctrine/persistence": "^1.3|^2.0",
         "symfony/asset": "^5.3",
         "symfony/browser-kit": "^4.4|^5.0",
diff --git a/src/Symfony/Bundle/TwigBundle/composer.json b/src/Symfony/Bundle/TwigBundle/composer.json
index 0c1b269ce6..1d9b1cb12e 100644
--- a/src/Symfony/Bundle/TwigBundle/composer.json
+++ b/src/Symfony/Bundle/TwigBundle/composer.json
@@ -37,7 +37,7 @@
         "symfony/framework-bundle": "^5.0",
         "symfony/web-link": "^4.4|^5.0",
         "doctrine/annotations": "^1.10.4",
-        "doctrine/cache": "~1.0"
+        "doctrine/cache": "^1.0|^2.0"
     },
     "conflict": {
         "symfony/dependency-injection": "<5.3",
diff --git a/src/Symfony/Component/Cache/composer.json b/src/Symfony/Component/Cache/composer.json
index 9b61e71108..6917879105 100644
--- a/src/Symfony/Component/Cache/composer.json
+++ b/src/Symfony/Component/Cache/composer.json
@@ -32,7 +32,7 @@
     },
     "require-dev": {
         "cache/integration-tests": "dev-master",
-        "doctrine/cache": "^1.6",
+        "doctrine/cache": "^1.6|^2.0",
         "doctrine/dbal": "^2.10|^3.0",
         "predis/predis": "^1.1",
         "psr/simple-cache": "^1.0",
diff --git a/src/Symfony/Component/Serializer/composer.json b/src/Symfony/Component/Serializer/composer.json
index 6662139bcc..60a0567f92 100644
--- a/src/Symfony/Component/Serializer/composer.json
+++ b/src/Symfony/Component/Serializer/composer.json
@@ -23,7 +23,6 @@
     },
     "require-dev": {
         "doctrine/annotations": "^1.12",
-        "doctrine/cache": "~1.0",
         "phpdocumentor/reflection-docblock": "^3.2|^4.0|^5.0",
         "symfony/cache": "^4.4|^5.0",
         "symfony/config": "^4.4|^5.0",
diff --git a/src/Symfony/Component/Validator/Tests/ValidatorBuilderTest.php b/src/Symfony/Component/Validator/Tests/ValidatorBuilderTest.php
index 8da875ebc8..71057ac8f0 100644
--- a/src/Symfony/Component/Validator/Tests/ValidatorBuilderTest.php
+++ b/src/Symfony/Component/Validator/Tests/ValidatorBuilderTest.php
@@ -12,6 +12,7 @@
 namespace Symfony\Component\Validator\Tests;
 
 use Doctrine\Common\Annotations\CachedReader;
+use Doctrine\Common\Annotations\PsrCachedReader;
 use Doctrine\Common\Annotations\Reader;
 use PHPUnit\Framework\TestCase;
 use Psr\Cache\CacheItemPoolInterface;
@@ -99,7 +100,11 @@ class ValidatorBuilderTest extends TestCase
         $r = new \ReflectionProperty(AnnotationLoader::class, 'reader');
         $r->setAccessible(true);
 
-        $this->assertInstanceOf(CachedReader::class, $r->getValue($loaders[0]));
+        if (class_exists(PsrCachedReader::class)) {
+            $this->assertInstanceOf(PsrCachedReader::class, $r->getValue($loaders[0]));
+        } else {
+            $this->assertInstanceOf(CachedReader::class, $r->getValue($loaders[0]));
+        }
     }
 
     public function testEnableAnnotationMappingWithDefaultDoctrineAnnotationReader()
@@ -114,7 +119,11 @@ class ValidatorBuilderTest extends TestCase
         $r = new \ReflectionProperty(AnnotationLoader::class, 'reader');
         $r->setAccessible(true);
 
-        $this->assertInstanceOf(CachedReader::class, $r->getValue($loaders[0]));
+        if (class_exists(PsrCachedReader::class)) {
+            $this->assertInstanceOf(PsrCachedReader::class, $r->getValue($loaders[0]));
+        } else {
+            $this->assertInstanceOf(CachedReader::class, $r->getValue($loaders[0]));
+        }
     }
 
     /**
diff --git a/src/Symfony/Component/Validator/ValidatorBuilder.php b/src/Symfony/Component/Validator/ValidatorBuilder.php
index 8b363b5539..eb9e536c8b 100644
--- a/src/Symfony/Component/Validator/ValidatorBuilder.php
+++ b/src/Symfony/Component/Validator/ValidatorBuilder.php
@@ -13,11 +13,13 @@ namespace Symfony\Component\Validator;
 
 use Doctrine\Common\Annotations\AnnotationReader;
 use Doctrine\Common\Annotations\CachedReader;
+use Doctrine\Common\Annotations\PsrCachedReader;
 use Doctrine\Common\Annotations\Reader;
 use Doctrine\Common\Cache\ArrayCache;
+use Doctrine\Common\Cache\Psr6\DoctrineProvider;
 use Psr\Cache\CacheItemPoolInterface;
 use Symfony\Component\Cache\Adapter\ArrayAdapter;
-use Symfony\Component\Cache\DoctrineProvider;
+use Symfony\Component\Cache\DoctrineProvider as SymfonyDoctrineProvider;
 use Symfony\Component\Validator\Context\ExecutionContextFactory;
 use Symfony\Component\Validator\Exception\ValidatorException;
 use Symfony\Component\Validator\Mapping\Factory\LazyLoadingMetadataFactory;
@@ -268,11 +270,7 @@ class ValidatorBuilder
      */
     public function addDefaultDoctrineAnnotationReader(): self
     {
-        if (class_exists(ArrayAdapter::class)) {
-            $this->annotationReader = new CachedReader(new AnnotationReader(), new DoctrineProvider(new ArrayAdapter()));
-        } else {
-            $this->annotationReader = new CachedReader(new AnnotationReader(), new ArrayCache());
-        }
+        $this->annotationReader = $this->createAnnotationReader();
 
         return $this;
     }
@@ -425,4 +423,39 @@ class ValidatorBuilder
 
         return new RecursiveValidator($contextFactory, $metadataFactory, $validatorFactory, $this->initializers);
     }
+
+    private function createAnnotationReader(): Reader
+    {
+        if (!class_exists(AnnotationReader::class)) {
+            throw new LogicException('Enabling annotation based constraint mapping requires the packages doctrine/annotations and symfony/cache to be installed.');
+        }
+
+        // Doctrine Annotation >= 1.13, Symfony Cache
+        if (class_exists(PsrCachedReader::class) && class_exists(ArrayAdapter::class)) {
+            return new PsrCachedReader(new AnnotationReader(), new ArrayAdapter());
+        }
+
+        // Doctrine Annotations < 1.13, Doctrine Cache >= 1.11, Symfony Cache
+        if (class_exists(CachedReader::class) && class_exists(DoctrineProvider::class) && class_exists(ArrayAdapter::class)) {
+            return new CachedReader(new AnnotationReader(), DoctrineProvider::wrap(new ArrayAdapter()));
+        }
+
+        // Doctrine Annotations < 1.13, Doctrine Cache < 1.11, Symfony Cache
+        if (class_exists(CachedReader::class) && !class_exists(DoctrineProvider::class) && class_exists(ArrayAdapter::class)) {
+            return new CachedReader(new AnnotationReader(), new SymfonyDoctrineProvider(new ArrayAdapter()));
+        }
+
+        // Doctrine Annotations < 1.13, Doctrine Cache < 1.11
+        if (class_exists(CachedReader::class) && class_exists(ArrayCache::class)) {
+            return new CachedReader(new AnnotationReader(), new ArrayCache());
+        }
+
+        // Doctrine Annotation >= 1.13, Doctrine Cache >= 2, no Symfony Cache
+        if (class_exists(PsrCachedReader::class)) {
+            throw new LogicException('Enabling annotation based constraint mapping requires the package symfony/cache to be installed.');
+        }
+
+        // Doctrine Annotation (<1.13 || >2), no Doctrine Cache, no Symfony Cache
+        throw new LogicException('Enabling annotation based constraint mapping requires the packages doctrine/annotations (>=1.13) and symfony/cache to be installed.');
+    }
 }
diff --git a/src/Symfony/Component/Validator/composer.json b/src/Symfony/Component/Validator/composer.json
index d9ca4a648e..119e90b03f 100644
--- a/src/Symfony/Component/Validator/composer.json
+++ b/src/Symfony/Component/Validator/composer.json
@@ -41,7 +41,7 @@
         "symfony/property-info": "^5.3",
         "symfony/translation": "^4.4|^5.0",
         "doctrine/annotations": "^1.10.4",
-        "doctrine/cache": "~1.0",
+        "doctrine/cache": "^1.0|^2.0",
         "egulias/email-validator": "^2.1.10|^3"
     },
     "conflict": {